教員紹介

氏名 伊東 秀之 ITO, Hideyuki
職位 教授
E-Mail hito●fhw.oka-pu.ac.jp
研究室番号 6204(研究室HP

担当科目
【共通教育】
基礎有機化学,環境の科学,化学の世界,自然科学入門(オムニバス)
【学部】
食品学Ⅰ,食品学Ⅱ,食品学実験Ⅰ,総合演習Ⅲ(オムニバス)
【博士前期】
食品機能学特論Ⅰ,食品機能学特論演習Ⅰ,食品栄養学特別研究,保健福祉学特論Ⅰ(オムニバス)
【博士後期】
食品機能科学特別講義,栄養学特別研究
研究テーマ
  1. 食品素材に含まれる機能性成分の単離および化学構造研究
  2. 機能性食品成分の分析法の開発
  3. 機能性ポリフェノール成分の生体利用性に関する研究
主な研究業績
  1. Kawabe, S., Ganeko, N., and Ito, H. (2017) Ellagitannin Dimers from Pericarps of Trapa japonica, The Japanese Journal of Pharmacognosy, 71, 53-54.
  2. Tai, A., Ohno, A., and Ito, H. (2016) Isolation and Characterization of the 2,2'-Azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) Radical Cation-Scavenging Reaction Products of Arbutin, J. Agric. Food Chem., 64 7285-7290.
  3. Zhao, C., Sakaguchi, T., Fujita, K., Ito, H., Nishida, N., Nagatomo, A., Tanaka-Azuma, Y., and Katakura, Y. (2016) Pomegranate-Derived Polyphenols Reduce Reactive Oxygen Species Production via SIRT3-Mediated SOD2 Activation, Oxid. Med. Cell Longev., 2016 Article ID 2927131, 9 pages.
  4. Ishimata, N., Ito, H., Tai, A. (2016) Structure–activity relationships of vanillic acid ester analogs in inhibitory effect of antigen-mediated degranulation in rat basophilic leukemia RBL-2H3 cells, Bioorg. Med. Chem. Lett., 26 3533-3536.
  5. Morita, A., Tai, A., Ito, H., Ganeko, N., and Aizawa, S-I., Proanthocyanidins in an astringent persimmon inhibit Salmonella pathogenicity island 1 (SPI1) secretion, J. Sci. Food Agric., 96, 1798-1802 (2016).
  6. Yagi, M., Mitsuhashi, R., Watanabe, A., Moritani, Y., Naito, J., Lanny, P., Ito, H., Nagatomo, A., Nishida, N., Yonei, Y., Cleaving effect of pomegranate (Punica granatum) extract on crosslink derived from advanced glycation endproducts, Glycative Stress Res., 2, 58-66 (2015).
  7. Arunrattiyakorn, P., Suwannasai, N., Aree, T., Kanokmedhakul, S., Ito, H., Kanzaki, H., Biotransformation of α-mangostin by Colletotrichum sp. MT02 and Phomopsis euphorbiae K12, J. Mol. Catal. B: Enzym., 102, 174-179 (2014).
  8. Asano, R., Nagami, A., Fukumoto, Y., Miura, K., Yazama, F., Ito, H., Sakata, I., Tai, A., Synthesis and biological evaluation of new boron-containing chlorin derivatives as agents for both photodynamic therapy and boron neutron capture therapy of cancer, Bioorg. Med. Chem. Lett., 24, 1339-1343 (2014).
  9. Ito, H., Peng, L., Koreishi, M., Nagatomo, A., Nishida, N., and Yoshida, T., Ellagitannin oligomers and a neolignan from pomegranate arils and their inhibitory effects on the formation of advanced glycation end products, Food Chem., 152, 323-330 (2014).
  10. Kawasaki, T., Ito, H., Omote, H., Components of foods inhibit a drug exporter, human multidrug and toxin extrusion transporter 1, Biol. Pharm. Bull., 37 (2), 292-297 (2014).
  11. Tominaga, H., Ishihara, T., Shah, A.K.M.A., Shimizu, R., Onyango, A.N., Ito, H., Suzuki, T., Kondo, Y., Koaze, H., Takahashi, K., Baba, N., Molecular probes in tandem electrospray ionization mass spectrometry: Application to tracing chemical changes of specific phospholipid molecular species, Am. J. Anal. Chem., 4, 16-26 (2013).
  12. Yamaguchi, S., Hirokane, T., Yoshida, T., Tanaka, T., Hatano, T., Ito, H., Nonaka, G., and Yamada, H., Roxbin B is cuspinin: Structural revision and total synthesis, J. Org. Chem., 78, 5410-5418 (2013).
  13. Kwon, O. J., Bae, J.-S., Lee, H. Y., Hwang, J.-Y., Lee, E.-W., Ito, H., and Kim, T. H., Pancreatic lipase inhibitory gallotannins from Galla rhois with inhibitory effects on adipocyte differentiation in 3T3-L1 cells, Molecules, 18, 10629-10638 (2013).
  14. Tai, A., Iwaoka, Y., Ito, H., Highly efficient and regioselective production of an erythorbic acid glucoside using cyclodextrin glucanotransferase from Thermoanaerobacter sp. and amyloglucosidase, J. Mol. Catal. B Enzym., 92, 19-23 (2013).
  15. Ito, H., Otsuki, A., Mori, H., Li, P., Kinoshita, M., Kawakami, Y., Tsuji, H., Fang, D.Z., Takahashi, Y., Two new monoterpene glycosides from Qing Shan Lu Shui tea with inhibitory effects on leukocyte-type 12-lipoxygenase activity, Molecules, 18, 4257-4266 (2013).
  16. Waha, L.K., Abasb, F., Cordelld G.A., Ito, H., and Ismail I.S., Steroids from Dysoxylum grande (Meliaceae) leaves, Steroids, 78, 210-219 (2013).
  17. Asano, R., Nagami, A., Fukumoto, Y., Yazama, F., Ito, H., Sakata, I., Tai, A., Synthesis and biological evaluation of new chlorin derivatives as potential photosensitizers for photodynamic therapy, Bioorg. Med. Chem., 21, 2298-2304 (2013).
  18. Nagano, T., Ito, H., and Okamoto, T., Inhibitory effect of ellagitannin metabolites on IgE-mediated allergic responses in RBL-2H3 cells, Biosci. Biotech. Biochem., 76, 2310-2312 (2012).
  19. Kirino, A., Takasuka, Y, Nishi, H., Kawabe, S., Yamashita, H., Kimoto, M., Ito, H., and Tsuji, H., Analysis and functionality of major polyphenolic components of Polygonum cuspidatum (Itadori), J. Nutr. Sci. Vitaminol., 58, 278-286 (2012).
  20. Kurasawa, Y., Yoshida, K., Yamazaki, N., Kaji, E., Sasaki, K., Zamami, Y., Sakai, Y., Fujii, T., and Ito, H., Quinolone analogs 11: Synthesis of novel 4-quinolone-3-carbohydrazide derivatives with antimalarial activity, J. Heterocyclic Chem., 49, 288-292 (2012).
  21. Tai, A., Ikeda, S., Yazama, F., and Ito, H., Intramolecular acyl migration and enzymatic hydrolysis of 2-O-α-D-glucopyranosyl-6-O-(2-pentylheptanoyl)-L-ascorbic acid, J. Biosci. Bioeng., 113, 545-548 (2012).
  22. Ishimoto, H., Tai, A., Yoshimura, M., Amakura, Y., Yoshida, T., Hatano, T., and Ito, H., Antioxidative properties of functional polyphenols and their metabolites assessed by an ORAC assay, Biosci. Biotech. Biochem., 76, 395-399 (2012).
  23. Tai, A., Sawano, T., Ito, H., Antioxidant properties of vanillic acid esters in multiple antioxidant assays, Biosci. Biotech. Biochem., 76, 314-318 (2012).
主な所属学会 日本農芸化学会,日本薬学会,日本生薬学会,日本栄養・食糧学会,日本食品化学学会,日本フードファクター学会

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