教員紹介

氏名 田中 晃一 TANAKA, Koichi
職位 准教授
E-Mail ktanaka●fhw.oka-pu.ac.jp
研究室番号 6212

専門分野 分子生物学、微生物学
担当科目
【学部】
分子生物学、微生物学、食品衛生学、微生物学実験、食品衛生学実験、みぢかなバイオテクノロジー
【博士前期】
応用微生物学特論、応用微生物学特論演習、保険福祉学特論Ⅲ、食品栄養学特別研究、災害医療援助特論演習
【博士後期】
遺伝子工学特別講義、食品栄養学特別研究
研究テーマ
  1. 新たな特性や機能性を有する発酵食品を製造するための微生物の探索・育種開発
  2. バイオマスエネルギーの製造を効率化するための微生物の探索・育種開発
主な業績
  1. Yoko Yoshiyama, Koichi Tanaka, Kohei Yoshiyama, Makoto Hibi, Jun Ogawa, and Jun Shima
    Trehalose accumulation enhances tolerance of Saccharomyces cerevisiae to acetic acid.
    J. Biosci. Bioeng. 119 (2), 172-175. (2015)
  2. Anthony M. Poole, Nobuyuki Horinouchi, Ryan J. Catchpole, Dayong Si, Makoto Hibi, Koichi Tanaka, Jun Ogawa
    The Case for an Early Biological Origin of DNA
    J. Mol. Evol. 79, 204–212. (2014)
  3. Takuya Inaba, Daisuke Watanabe, Yoko Yoshiyama, Koichi Tanaka, Jun Ogawa and Jun Shima
    An organic acid-tolerant HAA1-overexpression mutant of an industrial bioethanol strain of Saccharomyces cerevisiae and its application to the production of bioethanol from sugarcane molasses.
    AMB express, 3 (1), 74. (2013)
  4. Koichi Tanaka, Yukari Ishii, Jun Ogawa and Jun Shima
    Enhancement of acetic acid tolerance in Saccharomyces cerevisiae by overexpression of the HAA1 gene, encoding a transcriptional activator.
    Appl. Environ. Microbiol. 78 (22), 8161-8163. (2012)
  5. Sonoko Hasegawa, Tomoo Ogata, Koichi Tanaka, Akira Ando, Hiroshi Takagi and Jun Shima
    Overexpression of vacuolar H+-ATPase-related genes in bottom-fermenting yeast enhances ethanol tolerance and fermentation rates during high-gravity fermentation.
    J. Inst. Brew. 118 (2), 179-185. (2012)
  6. Yutaka Haitani*, Koichi Tanaka*, Mami Yamamoto, Toshihide Nakamura, Akira Ando, Jun Ogawa and Jun Shima (*These authors contributed equally to this work)
    Identification of an acetate-tolerant strain of Saccharomyces cerevisiae and characterization by gene expression analysis.
    J. Biosci. Bioeng. 114 (6), 648-651. (2012)
  7. Ayano Kagami, Takeshi Sakuno, Yuya Yamagishi, Tadashi Ishiguro, Tatsuya Tsukahara, Katsuhiko Shirahige, Koichi Tanaka and Yoshinori Watanabe
    Acetylation regulates monopolar attachment at multiple levels during meiosis I in fission yeast.
    EMBO Rep. 12(11), 1189-1195. (2011)
  8. Takeshi Sakuno, Koichi Tanaka, Silke Hauf and Yoshinori Watanabe
    Repositioning of Aurora B promoted by chiasmata ensures sister chromatid mono-orientation in meiosis I.
    Dev. Cell. 21 (3), 534–545. (2011)
  9. Tadashi Ishiguro, Koichi Tanaka, Takeshi Sakuno and Yoshinori Watanabe
    Shugoshin-PP2A counteracts casein-kinase-1-dependent cleavage of Rec8 by separase.
    Nat. Cell Biol. 12 (5), 500-506. (2010)
  10. Koichi Tanaka, Hui Li Chang, Ayano Kagami and Yoshinori Watanabe
    CENP-C functions as a scaffold for effectors with essential kinetochore functions in mitosis and meiosis.
    Dev. Cell. 17 (3), 334-343. (2009)
  11. Koichi Tanaka and Yoshinori Watanabe
    Chromatid cohesion: acetylation joins the sisters.
    Curr. Biol. 18 (19), R917-919. (2008)
  12. Koichi Tanaka and Yoshinori Watanabe
    Sister chromatid cohesion and centromere organization in meiosis.
    Series Genome Dynamics and Stability, Vol. 2, Recombination and meiosis. Crossing-over and Disjunction. (Eds.: Egel, R and Lankenau, D.)
    Springer-Verlag, Berlin Heidelberg, 57-79. (2007)
  13. Naoto Matsuda, Hiroko Tanaka, Sanae Yamazaki, Jun-ichiro Suzuki, Koichi Tanaka, Takeshi Yamada and Michiaki Masuda
    HIV-1 Vpr induces G2 cell cycle arrest in fission yeast associated with Rad24/14-3-3-dependent, Chk1/Cds1-independent Wee1 upregulation.
    Microbes Infect. 8 (12-13), 2736-2744. (2006)
  14. Erwan Watrin, Alexsander Schleiffer, Koichi Tanaka, Frank Eisenhaber, Kim Nasmyth and Jan-Michael Peters
    Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression.
    Curr. Biol. 16 (9), 863-874. (2006)
  15. Foong May Yeong, Hans Hombauer, Kerstin S. Wendt, Toru Hirota, Ingrid Mudrak, Karl Mechtler, Thomas Loregger, Aron Marchler-Bauer, Koichi Tanaka, Jan-Michael Peters and Egon Ogris
    Identification of a subunit of a novel Kleisin-beta/SMC complex as a potential substrate of protein phosphatase 2A.
    Curr. Biol. 13 (23), 2058-2064. (2003)
  16. Prakash Arumugam, Stephan Gruber, Koichi Tanaka, Christian H. Haering, Karl Mechtler and Kim Nasmyth
    ATP hydrolysis is required for cohesin's association with chromosomes.
    Curr. Biol., 13 (22), 1941-1953. (2003)
  17. Hiroyuki Tanaka, Gi-Hyuck Ryu, Yeon-Soo Seo, Koichi Tanaka, Hiroto Okayama, Stuart A. MacNeill, and Yasuhito Yuasa
    The fission yeast pfh1(+) gene encodes an essential 5' to 3' DNA helicase required for the completion of S-phase.
    Nucleic Acids Res., 30 (21), 4728-4739. (2002)
  18. Koichi Tanaka, Zhonglin Hao, Mihoko Kai and Hiroto Okayama
    Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism.
    EMBO J., 20 (20), 5779-5790. (2001)
  19. Koichi Tanaka and Hiroto Okayama
    A Pcl-like cyclin activates the Res2-Cdc10 cell cycle 'start' transcriptional factor complex in fission yeast.
    Mol. Biol. Cell, 11 (9), 2845-2862. (2000)
  20. Koichi Tanaka, Toshihiro Yonekawa, Yosuke Kawasaki, Mihoko Kai, Kanji Furuya, Masaomi Iwasaki, Hiroshi Murakami, Mitsuhiro Yanagida and Hiroto Okayama
    Fission yeast Eso1p is required for establishing sister chromatid cohesion during S phase.
    Mol. Cell. Biol., 20 (10), 3459-3469. (2000)
  21. Michiaki Masuda, Yukiko Nagai, Norihito Oshima, Koichi Tanaka, Hiroshi Murakami and Hiroto Okayama
    Genetic studies using the fission yeast Schizosaccharomyces pombe suggest involvement of wee1, ppa2, and rad24 in induction of cell cycle arrest by human immunodeficiency virus type 1 Vpr.
    J. Virol., 74 (6), 2636-2646. (2000)
  22. Hiroyuki Tanaka, Koichi Tanaka, Hiroshi Murakami and Hiroto Okayama
    Fission yeast Cdc24 is an RFC- and PCNA-interacting factor essential for S phase completion.
    Mol. Cell. Biol., 19 (2), 1038-1048. (1999)
  23. Sayaka Tahara, Koichi Tanaka, Yasuhito Yuasa and Hiroto Okayama
    Functional domains of Rep2, a transcriptional activator subunit for Res2-Cdc10, controlling the cell cycle "start".
    Mol. Biol. Cell. 9 (6), 1577-1588. (1998)
  24. Seiji Horie, Yoshinori Watanabe, Koichi Tanaka, Shinya Nishiwaki, Hiroshi Fujioka, Hiroko Abe, Masayuki Yamamoto and Chikashi Shimoda
    The Schizosaccharomyces pombe mei4+ gene encodes a meiosis-specific transcription factor containing a forkhead DNA-binding domain.
    Mol. Cell. Biol. 18 (4), 2118-2129. (1998)
  25. Hiroto Okayama, Akihisa Nagata, Shigeki Jinno, Hiroshi Murakami, Koichi Tanaka and Naomi Nakashima
    Cell cycle control in fission yeast and mammals: Identification of new regulatory mechanisms.
    Adv. Cancer Res. 69, 17-62. (1996)
  26. Naomi Nakashima, Koichi Tanaka, Sabine Sturm and Hiroto Okayama
    Fission yeast Rep2 is a putative transcriptional activator subunit for the cell cycle 'start' function of Res2-Cdc10.
    EMBO J. 14 (19), 4794-4802. (1995)
  27. Masaaki Miyamoto, Koichi Tanaka and Hiroto Okayama
    res2+, a new member of cdc10+/SWI4 family, controls the "start" of mitotic and meiotic cycles in fission yeast.
    EMBO J. 13 (8), 1873-1880. (1994)
  28. Akio Sugiyama, Koichi Tanaka, Koei Okazaki, Hiroshi Nojima and Hiroto Okayama
    A zinc finger protein controls the onset of premeiotic DNA synthesis of fission yeast in a Mei2-independent cascade.
    EMBO J. 13 (8), 1881-1887. (1994)
  29. Koichi Tanaka, Koei Okazaki, Noriko Okazaki, Toru Ueda, Akio Sugiyama, Hiroshi Nojima and Hiroto Okayama
    A new cdc gene required for S phase entry of Schizosaccharomyces pombe encodes a protein similar to the cdc10+ and SWI4 gene products.
    EMBO J. 11 (13), 4923-4932. (1992)
  30. Noriko Okazaki, Koei Okazaki, Koichi Tanaka and Hiroto Okayama
    The ste4+ gene, essential for sexual differentiation of Schizosaccharomyces pombe, encodes a protein with a leucine zipper motif.
    Nucleic Acids Res. 19 (25), 7043-7047. (1991)
  31. Koei Okazaki, Noriko Okazaki, Kazuhiko Kume, Shigeki Jinno, Koichi Tanaka and Hiroto Okayama
    High-frequency transformation method and library transducing vectors for cloning mammalian cDNAs by trans-complementation of Schizosaccharomyces pombe.
    Nucleic Acids Res. 18 (22), 6485-6489. (1990)

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